At 17.42% CAGR, Oligonucleotide Synthesis Market Size is Expected to Reach USD 22584.1 Million in 2028, says Brandessence Market Research

LondonAnd January 17 2022 /PRNewswire/ – Global market value for oligonucleotide synthesis estimated 7338.5 million US dollars In 2021 it is expected to arrive 22584.1 Million USD by 2028 at a compound annual growth rate of 17.42% over the forecast period. Increasing government investment in synthetic biology and genomics projects and the growing need for oligo products are some of the key factors driving the growth of the global market for oligonucleotide synthesis by Brandessence Market Research & Consulting Pvt ltd.

The Brandessence research team carefully observed the impact of Covid-19 on the global oligonucleotide synthesis market, and it is conceivable that the demand for oligonucleotide synthesis has increased during the pandemic period. To control the crushing spread of Covid-19, many countries around the world have imposed strict lockdown standards, which have hampered many types of business activities. However, there has also been a building and demand flow effect on many medical services, including oligonucleotide products. Several players in the oligonucleotide synthesis market are stepping forward to contribute to the global research effort by offering oligo products for the development of therapeutics, test kits and vaccines.

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Scope of the Global Oligonucleotide Synthesis Market Report:

Oligonucleotides are short molecules of RNA or DNA, oligomers that are used as probes for observing the exact complementary sequences of oligonucleotides. Oligonucleotides have a wide range of applications in research, genetic testing, and forensic medicine. Oligonucleotide synthesis is the synthesis of fairly small fragments of nucleic acids that is carried out chemically with a specific chemical composition (sequence). This technique provides rapid and inexpensive access to an on-demand oligonucleotide of the preferred sequence. Oligonucleotide synthesis is also useful in making molecular diagnostics of many diseases, accounting for the detection of infectious diseases, such as SARS-COV2 and hepatitis as well as for the diagnosis of cancer. These are generally used in laboratories in various applications such as diagnosis, treatment, academic as well as industrial. They are used from early research and screening through to targeted verification and drug manufacturing. At present, a number of improvements in oligonucleotide synthesis, automation and amplification have revolutionized biological research. It is also possible to make customizations and get the desired sequence online effortlessly and on time. In the fifties of the last century, Alexander Todd The group established H-phosphonate and phosphate triester approaches to synthesis of oligonucleotide.

Global market dynamics for oligonucleotide synthesis:

The increase in demand for oligo products for the treatment of Covid-19 is one of the main factors driving the growth of the oligonucleotide synthesis market. The Covid-19 outbreak has disrupted the functioning of the healthcare sector across the world. However, there has also been an optimistic effect and an increase in demand for many medical services, which contain oligonucleotide products. Oligo products are mainly used to improve treatments, test kits, and vaccines targeting the novel coronavirus infection. In addition, with the increase in the incidence of coronavirus diseases, new generations of oligonucleotide drugs are currently being developed, including RNA and DNA vaccines. Besides, with the intensification of cases of coronavirus disease and the urgent need for potential treatment, new generations of oligonucleotide drugs, containing mRNA and DNA vaccines, are currently underway. for example; in a April 2020, in order to advance the Covid-19 vaccine, TriLink BioTechnologies has partnered with Imperial College London to manufacture self-amplifying RNA (saRNA) and has also brought ready-to-use mixes such as SARS-CoV-2 N2 Oligo Mix, SARS-CoV-2 N1 Oligo Mix and Human RNase P(RP) Oligo Mix for Covid-19 research.

Moreover, governments in many countries have made noteworthy investments in projects related to the field of synthetic biology and genomics. These government investments have played a major role in expanding innovative technologies. Oligos plays a vital role in these technologies, therefore, increased funding and improvements in these areas are also fueling market growth. for example; The Department of Biotechnology (DBT) established the “India Genome Project” in January 2020. This scheme aims to collect about 10,000 genetic samples from citizens through India To construct a reference genome. In addition, the UK’s Center for Process Innovation has launched a project at the Pharmaceutical Manufacturing Innovation Center in February 2021. This scheme aims to revolutionize oligonucleotide engineering on collaboration with Novartis, AstraZeneca, Exactmer and UK Research & Innovation. Such government-sponsored projects will lead to improvements in genetic technologies, specifically in DNA sequencing, DNA amplification, NGS, and gene expression. Hence, this factor plays the major role in the growth of the oligonucleotide synthesis market.

Some of the major players for global oligonucleotide synthesis are:

  • Al-Nilam Pharmaceutical Company
  • Biogen Corporation
  • Danaher Corporation
  • Eurofins Scientific
  • Ionis Pharmaceuticals, Inc.
  • Kanika Company
  • LGC Limited
  • Merck Kja
  • Sarepta Therapeutics, Inc.
  • Thermo Fisher Scientific, Inc.
  • Others also contribute to the oligonucleotide synthesis market

News: Biotage DNA Synthesis and Purification Company Acquires ATDBio

employment October 20 2021Biotage, a Swedish drug analytics and discovery company, has reached an agreement to acquire shares in UK-based ATDBio Limited (ATDBio), for a total price of approximately £45 million. ATDBio promotes important platform solutions for biotags within the synthesis and purification of DNA and RNA oligonucleotides. This acquisition is expected to strengthen Biotage as a pre-eminent life sciences tool and technology service provider with an impact.

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Oligonucleotide synthesis key fragmentation analysis:

High School:

  • Medicines containing oligonucleotides
  • complex oligonucleotides
  • reagents
  • Tools

By applications:

  • therapeutic applications
  • search apps
  • Diagnostic applications

By end users:

  • Hospitals
  • Pharma and biotechnology companies
  • Diagnostic laboratories
  • CROs and CMOs
  • Academic Research Institutes

By type of disease:

  • Neurological disorders
  • Infectious diseases
  • Other diseases

Regional Analysis of the Global Oligonucleotide Synthesis Market:

Geography , North America It is expected to represent the largest share in the global oligonucleotide synthesis market during the forecast period which is attributed to increased R&D in life sciences, increased focus on improving health care safety and quality, and many other factors. The presence of several global players in this region is the main factor contributing to this market segment. Danaher Corporation and Thermo Fisher Scientific, Inc. And Maravai Life Sciences and several other players pumped millions into the oligonucleotide synthesis market. Apart from these, a number of small and medium-sized players are also benefiting from this market. for example; employment 29 July 2019; Twist Bioscience Corporation announces the release of long oligonucleotides. Withal, Biotage Company acquires UK-based Oligo Maker ATDBio for £45m in cash and stock October 20 2021. Many other companies that are not even from the US have a large presence in the US Likewise, many players from the oligonucleotide synthesis market have greatly expanded their business in this region. Therefore, this intensively promotes market growth for oligonucleotide synthesis.

Also, Asia Pacific It is the fastest growing region in the oligonucleotide synthesis market due to the sudden rise in cases of chronic disorders such as Covid-19, coronary artery disease, cancer, among others. for example; According to the World Cancer Research Fund; Highest rate of cancer in South Korea for men and women together 313.5 people per 100,000. Moreover, according to the Worlometer, on January 10 2022, Asia Pacific has reported more than 86,888,347 total cases of Covid-19, of which nearly 1,263,870 have caused death. As the number of chronic diseases is increasing day by day, the need for treatment with them increases exponentially. To a large extent, oligonucleotides are an emerging treatment modality for many common diseases such as Covid-19, coronary artery disease. Therefore, the market value of oligonucleotide synthesis flourishes in this region and makes Asia Pacific The fastest growing region worldwide.

As per special requirement, Oligonucleotide Synthesis market report is also available for the following region:

North America


  • Germany, France, United Kingdom, Italy, Spain, Sweden, Netherlands, Turkey, Switzerland, Belgium, Rest of Europe

Asia Pacific

  • South Korea, Japan, China, India, Australia, Philippines, Singapore, Malaysia, Thailand, Indonesia and the rest of Asia Pacific,

Latin america

  • Mexico, Colombia, Brazil, Argentina, Peru and the rest of Latin America

Middle East and Africa

  • Kingdom Saudi Arabia, UAE, Egypt, South Africa, the rest of the Middle East and Africa

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